Vendhu Thanindhathu Kaadu follows Muthu, a young man from Thoothukudi who travels to Mumbai in search of work but gets drawn into the violent world of the Mumbai underworld. As he rises from a helpless migrant to a feared gangster, Muthu is forced to confront betrayal, survival, and the price of power. The film traces his transformation from innocence to inevitability, laying the foundation for a larger saga explored in the sequel.